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DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm

There is an increased prevalence of imprinting disorders, such as Beckwith–Wiedemann syndrome, associated with human assisted reproductive technologies (ART). Work on animal models suggests that in vitro culture may be the source of these imprinting errors. However, in this study we report that, in...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hisato, Hiura, Hitoshi, John, Rosalind M, Sato, Akiko, Otsu, Eiko, Kobayashi, Naoko, Suzuki, Rei, Suzuki, Fumihiko, Hayashi, Chika, Utsunomiya, Takafumi, Yaegashi, Nobuo, Arima, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845511/
https://ncbi.nlm.nih.gov/pubmed/19471309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.68
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