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Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer

BACKGROUND: Critical to successful execution of mitochondrial-mediated apoptosis is apoptosome formation and subsequent activation of caspases. Defects in this pathway have an important role in colorectal carcinogenesis and chemoresistance; therefore, the expression of apoptosome-associated proteins...

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Detalhes bibliográficos
Main Authors: Hector, S, Conlon, S, Schmid, J, Dicker, P, Cummins, R J, Concannon, C G, Johnston, P G, Kay, E W, Prehn, J H M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341858/
https://ncbi.nlm.nih.gov/pubmed/22481083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.133
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