Prognostic significance of TRAIL signalling molecules in Stage II and III colorectal cancer

PURPOSE: We previously found that c-FLIP, caspase 8 and TRAIL receptor 2 (DR5) are major regulators of cell viability and chemotherapy-induced apoptosis in colorectal cancer (CRC). In this study, we determined the prognostic significance of c-FLIP, caspase 8, TRAIL and DR5 expression in tissues from...

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Detalhes bibliográficos
Main Authors: McLornan, Donal P., Barrett, Helen L., Cummins, Robert, McDermott, Ultan, McDowell, Cliona, Conlon, Susie J., Coyle, Victoria M., Van Schaeybroeck, Sandra, Wilson, Richard, Kay, Elaine W., Longley, Daniel B., Johnston, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896551/
https://ncbi.nlm.nih.gov/pubmed/20570920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0052
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