Prognostic significance of TRAIL signalling molecules in Stage II and III colorectal cancer

PURPOSE: We previously found that c-FLIP, caspase 8 and TRAIL receptor 2 (DR5) are major regulators of cell viability and chemotherapy-induced apoptosis in colorectal cancer (CRC). In this study, we determined the prognostic significance of c-FLIP, caspase 8, TRAIL and DR5 expression in tissues from...

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Main Authors: McLornan, Donal P., Barrett, Helen L., Cummins, Robert, McDermott, Ultan, McDowell, Cliona, Conlon, Susie J., Coyle, Victoria M., Van Schaeybroeck, Sandra, Wilson, Richard, Kay, Elaine W., Longley, Daniel B., Johnston, Patrick G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896551/
https://ncbi.nlm.nih.gov/pubmed/20570920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0052
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