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The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer

The execution phase of apoptosis is a critical process in programmed cell death in response to a multitude of cellular stresses. A crucial component of this pathway is the apoptosome, a platform for the activation of pro-caspase 9 (PC9). Recent findings have shown that autocleavage of PC9 to Caspase...

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Detalles Bibliográficos
Publicado en:Cell Death Differ
Autores principales: Fullstone, Gavin, Bauer, Tabea L., Guttà, Cristiano, Salvucci, Manuela, Prehn, Jochen H. M., Rehm, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493894/
https://ncbi.nlm.nih.gov/pubmed/32341447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0545-9
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