Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo.
Subsequent to the discovery that RNA can have site specific cleavage activity, there has been a great deal of interest in the design and testing of trans-acting catalytic RNAs as both surrogate genetic tools and as therapeutic agents. We have been developing catalytic RNAs or ribozymes with target s...
Gardado en:
| Publicado en: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1992
|
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.17.4559 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|