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Ligand dependence of estrogen receptor induced changes in chromatin structure.

To determine whether the human estrogen receptor requires ligand to bind to its cognate estrogen receptor element (ERE) in vivo, we have examined the structure of chromatin at a chromosomally integrated ERE-URA3 reporter gene in yeast, and the influence of ligand bound and ligand free estrogen recep...

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Détails bibliographiques
Auteurs principaux: Gilbert, D M, Losson, R, Chambon, P
Format: Artigo
Langue:Inglês
Publié: 1992
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC334180/
https://ncbi.nlm.nih.gov/pubmed/1408752
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