Ligand-dependent activation of transcription in vitro by retinoic acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo

All-trans and 9-cis retinoic acids (RA) signals are transduced by retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers that act as functional units controlling the transcription of RA-responsive genes. With the aim of elucidating the underlying molecular mechanisms, we have developed an...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Dilworth, F. Jeffrey, Fromental-Ramain, Catherine, Remboutsika, Eumorphia, Benecke, Arndt, Chambon, Pierre
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.1995
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