Ligand-dependent activation of transcription in vitro by retinoic acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo

All-trans and 9-cis retinoic acids (RA) signals are transduced by retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers that act as functional units controlling the transcription of RA-responsive genes. With the aim of elucidating the underlying molecular mechanisms, we have developed an...

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Detalhes bibliográficos
Main Authors: Dilworth, F. Jeffrey, Fromental-Ramain, Catherine, Remboutsika, Eumorphia, Benecke, Arndt, Chambon, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26725/
https://ncbi.nlm.nih.gov/pubmed/10051583
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