Ligand dependence of estrogen receptor induced changes in chromatin structure.

To determine whether the human estrogen receptor requires ligand to bind to its cognate estrogen receptor element (ERE) in vivo, we have examined the structure of chromatin at a chromosomally integrated ERE-URA3 reporter gene in yeast, and the influence of ligand bound and ligand free estrogen recep...

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Bibliographic Details
Main Authors: Gilbert, D M, Losson, R, Chambon, P
Format: Artigo
Language:Inglês
Published: 1992
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC334180/
https://ncbi.nlm.nih.gov/pubmed/1408752
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