Reversal of in vitro p53 squelching by both TFIIB and TFIID.
p53, the protein encoded by one of the most significant human tumor suppressor genes, is a sequence-specific transcriptional activator. When activated by a double-stranded DNA break, p53 function arrests cells in G1 and can induce apoptosis. Transcriptional activation function is critical for p53 tu...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565799/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6474 |
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