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Intracellular Detection of Cytosine Incorporation in Genomic DNA Using 5-Ethynyl-2′-Deoxycytidine

5-Ethynyl-2′-deoxycytidine triphosphate (EdCTP) was synthesized as a probe to be used in conjunction with fluorescent labelling to facilitate the analysis of the in vivo dynamics of DNA-centered processes (DNA replication, repair and cytosine demethylation). Kinetic analysis showed that EdCTP is acc...

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Detalhes bibliográficos
Main Authors: Guan, Lirui, van der Heijden, Godfried W., Bortvin, Alex, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341615/
https://ncbi.nlm.nih.gov/pubmed/21805552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100353
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