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Determination of the Kinetic Profile of a Dinuclear Platinum Anticancer Complex in the Presence of Sulfate: Introducing a New Tool for the Expedited Analysis of 2D [(1)H, (15)N] HSQC NMR Spectra

Two-dimensional (2D)[(1)H, (15)N] heteronuclear single-quantum coherence (HSQC) NMR experiments of the kinetics of aquation and sulfation of the dinuclear platinum anticancer complex [{trans-PtCl(NH(3))(2)}(2)(μ-NH(2)(CH(2))(6)NH(2))](2+) (1,1/t,t, 1) in 15 mM sulfate solution are reported using con...

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Autors principals: Ruhayel, Rasha A., Corry, Ben, Braun, Carlos, Thomas, Donald S., Berners-Price, Susan J., Farrell, Nicholas P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341403/
https://ncbi.nlm.nih.gov/pubmed/21067174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic100576k
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