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Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells

Protection against P. berghei malaria can successfully be induced in mice by immunization with both radiation attenuated sporozoites (RAS) arresting early during liver stage development, or sporozoites combined with chloroquine chemoprophylaxis (CPS), resulting in complete intra-hepatic parasite dev...

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Hlavní autoři: Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Arens, Theo, Hermsen, Cornelus C., Sauerwein, Robert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341355/
https://ncbi.nlm.nih.gov/pubmed/22563506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036508
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