Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells

Protection against P. berghei malaria can successfully be induced in mice by immunization with both radiation attenuated sporozoites (RAS) arresting early during liver stage development, or sporozoites combined with chloroquine chemoprophylaxis (CPS), resulting in complete intra-hepatic parasite dev...

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Main Authors: Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Arens, Theo, Hermsen, Cornelus C., Sauerwein, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341355/
https://ncbi.nlm.nih.gov/pubmed/22563506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036508
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