Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria

BACKGROUND: Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria. In humans, CPS-CQ is strikingly more efficient than immunization with radiation attenuated sporozoites (RAS), raising the hypothe...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Bijker, Else M, Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Zavala, Fidel, Cockburn, Ian, Sauerwein, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389414/
https://ncbi.nlm.nih.gov/pubmed/25889324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0626-2
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