Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8(+ )T cell response in the liver

BACKGROUND: The induction of sterile immunity and long lasting protection against malaria has been effectively achieved by immunization with sporozoites attenuated by gamma-irradiation or through deletion of genes. For mice immunized with radiation attenuated sporozoites (RAS) it has been shown that...

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Detalhes bibliográficos
Main Authors: Douradinha, Bruno, van Dijk, Melissa, van Gemert, Geert-Jan, Khan, Shahid M, Janse, Chris J, Waters, Andy P, Sauerwein, Robert W, Luty, Adrian JF, Silva-Santos, Bruno, Mota, Maria M, Epiphanio, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206817/
https://ncbi.nlm.nih.gov/pubmed/22004696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-9-6
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