Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

Immunization with Plasmodium sporozoites that have been attenuated by γ-irradiation or specific genetic modification can induce protective immunity against subsequent malaria infection. The mechanism of protection is only known for radiation-attenuated sporozoites, involving cell-mediated and humora...

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Bibliografische gegevens
Hoofdauteurs: van Dijk, Melissa R., Douradinha, Bruno, Franke-Fayard, Blandine, Heussler, Volker, van Dooren, Maaike W., van Schaijk, Ben, van Gemert, Geert-Jan, Sauerwein, Robert W., Mota, Maria M., Waters, Andrew P., Janse, Chris J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189305/
https://ncbi.nlm.nih.gov/pubmed/16103357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500925102
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