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Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons
Recent studies have shown the involvement of cyclin-dependent kinase 5 (Cdk5) in cell cycle regulation in postmitotic neurons. In this study, we demonstrate that Cdk5 and its co-activator p35 were detected in the nuclear fraction in neurons and Cdk5/p35 phosphorylated retinoblastoma (Rb) protein, a...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341229/ https://ncbi.nlm.nih.gov/pubmed/22456337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20009 |
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