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Enhancing CHK1 inhibitor lethality in glioblastoma

The present studies were initiated to determine whether inhibitors of MEK1/2 or SRC signaling, respectively, enhance CHK1 inhibitor lethality in primary human glioblastoma cells. Multiple MEK1/2 inhibitors (CI-1040 (PD184352); AZD6244 (ARRY-142886)) interacted with multiple CHK1 inhibitors (UCN-01,...

詳細記述

保存先:
書誌詳細
主要な著者: Tang, Yong, Dai, Yun, Grant, Steven, Dent, Paul
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341214/
https://ncbi.nlm.nih.gov/pubmed/22313687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19240
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