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Torque measurements reveal sequence-specific cooperative transitions in supercoiled DNA

B-DNA becomes unstable under superhelical stress and is able to adopt a wide range of alternative conformations including strand-separated DNA and Z-DNA. Localized sequence-dependent structural transitions are important for the regulation of biological processes such as DNA replication and transcrip...

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Autors principals: Oberstrass, Florian C., Fernandes, Louis E., Bryant, Zev
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341030/
https://ncbi.nlm.nih.gov/pubmed/22474350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113532109
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