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Torque spectroscopy of DNA: base-pair stability, boundary effects, backbending, and breathing dynamics
Changes in global DNA linking number can be accommodated by localized changes in helical structure. We have used single-molecule torque measurements to investigate sequence-specific strand separation and Z-DNA formation. By controlling the boundary conditions at the edges of sequences of interest, w...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696636/ https://ncbi.nlm.nih.gov/pubmed/23679785 |
| Oznake: |
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