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Torque measurements reveal sequence-specific cooperative transitions in supercoiled DNA
B-DNA becomes unstable under superhelical stress and is able to adopt a wide range of alternative conformations including strand-separated DNA and Z-DNA. Localized sequence-dependent structural transitions are important for the regulation of biological processes such as DNA replication and transcrip...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341030/ https://ncbi.nlm.nih.gov/pubmed/22474350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113532109 |
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