Supercoiling-dependent sequence specificity of mammalian DNA methyltransferase.
Negative supercoiling of substrate DNA dramatically alters the in vitro sequence specificity of mammalian DNA methyltransferase (DNA MeTase). This result suggests that in vivo site selection by DNA MeTase could be regulated by conformational information in the form of alternative secondary structure...
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| Publicado no: | Nucleic Acids Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1987
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3473446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.9.3835 |
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