Supercoiling-dependent sequence specificity of mammalian DNA methyltransferase.
Negative supercoiling of substrate DNA dramatically alters the in vitro sequence specificity of mammalian DNA methyltransferase (DNA MeTase). This result suggests that in vivo site selection by DNA MeTase could be regulated by conformational information in the form of alternative secondary structure...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1987
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3473446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.9.3835 |
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