SOD1 suppresses maternal hyperglycemia-increased iNOS expression and consequent nitrosative stress in diabetic embryopathy

OBJECTIVES: Hyperglycemia induces oxidative stress and increases inducible nitric oxide synthase (iNOS) expression. We hypothesized that oxidative stress is responsible for hyperglycemia-induced iNOS expression. STUDY DESIGN: iNOS-luciferase activities, nitrosylated protein, lipidperoxidation marker...

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Main Authors: Weng, Hongbo, Li, Xuezheng, Reece, E. Albert, Yang, Peixin
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340508/
https://ncbi.nlm.nih.gov/pubmed/22425406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2012.02.011
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