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SOD1 suppresses maternal hyperglycemia-increased iNOS expression and consequent nitrosative stress in diabetic embryopathy
OBJECTIVES: Hyperglycemia induces oxidative stress and increases inducible nitric oxide synthase (iNOS) expression. We hypothesized that oxidative stress is responsible for hyperglycemia-induced iNOS expression. STUDY DESIGN: iNOS-luciferase activities, nitrosylated protein, lipidperoxidation marker...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340508/ https://ncbi.nlm.nih.gov/pubmed/22425406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2012.02.011 |
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