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Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation
The catalytic subunit of cAMP-dependent protein kinase (PKA) is a member of the AGC group of protein kinases. Whereas PKA has served as a structural model for the protein kinase superfamily, all previous structures of the catalytic subunit contain a phosphorylated activation loop. To understand the...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340281/ https://ncbi.nlm.nih.gov/pubmed/22334660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.335091 |
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