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Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

Lipotoxicity refers to the cytotoxic effects of excess fat accumulation in cells and has been implicated as one of the contributing factors to diseases like obesity, diabetes, and non-alcoholic fatty liver. In this study we sought to examine effects of palmitic acid (PA) and oleic acid, two of the c...

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Autors principals: Tan, Shi Hao, Shui, Guanghou, Zhou, Jing, Li, Jasmine Jia'En, Bay, Boon-Huat, Wenk, Markus R., Shen, Han-Ming
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340233/
https://ncbi.nlm.nih.gov/pubmed/22408252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294157
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