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Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

Lipotoxicity refers to the cytotoxic effects of excess fat accumulation in cells and has been implicated as one of the contributing factors to diseases like obesity, diabetes, and non-alcoholic fatty liver. In this study we sought to examine effects of palmitic acid (PA) and oleic acid, two of the c...

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Detalhes bibliográficos
Main Authors: Tan, Shi Hao, Shui, Guanghou, Zhou, Jing, Li, Jasmine Jia'En, Bay, Boon-Huat, Wenk, Markus R., Shen, Han-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340233/
https://ncbi.nlm.nih.gov/pubmed/22408252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294157
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