Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA

Phosphorylation of signal transducer and activator of transcription 3 (STAT3) on a single tyrosine residue in response to growth factors, cytokines, interferons, and oncogenes activates its dimerization, translocation to the nucleus, binding to the interferon γ (gamma)-activated sequence (GAS) DNA-b...

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Autori principali: Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshanamurthy, Sivanesan, Brown, Milton L., Dritschilo, Anatoly
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340179/
https://ncbi.nlm.nih.gov/pubmed/22378781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323899
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