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Crystal Structures of N-Acetylmannosamine Kinase Provide Insights into Enzyme Activity and Inhibition

Sialic acids are essential components of membrane glycoconjugates. They are responsible for the interaction, structure, and functionality of all deuterostome cells and have major functions in cellular processes in health and diseases. The key enzyme of the biosynthesis of sialic acid is the bifuncti...

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Autors principals: Martinez, Jacobo, Nguyen, Long Duc, Hinderlich, Stephan, Zimmer, Reinhold, Tauberger, Eva, Reutter, Werner, Saenger, Wolfram, Fan, Hua, Moniot, Sébastien
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340156/
https://ncbi.nlm.nih.gov/pubmed/22343627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318170
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