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A Novel Approach to Decrease Sialic Acid Expression in Cells by a C-3-modified N-Acetylmannosamine

Due to its position at the outermost of glycans, sialic acid is involved in a myriad of physiological and pathophysiological cell functions such as host-pathogen interactions, immune regulation, and tumor evasion. Inhibitors of cell surface sialylation could be a useful tool in cancer, immune, antib...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Wratil, Paul R., Rigol, Stephan, Solecka, Barbara, Kohla, Guido, Kannicht, Christoph, Reutter, Werner, Giannis, Athanassios, Nguyen, Long D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231682/
https://ncbi.nlm.nih.gov/pubmed/25278018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608398
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