Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is a bifunctional enzyme, which initiates and regulates sialic acid biosynthesis. Sialic acids are important compounds of mammalian glycoconjugates, mediating several biological processes, such as cell–cell or cell–matrix interactions. I...

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Main Authors: Blume, Astrid, Weidemann, Wenke, Stelzl, Ulrich, Wanker, Erich E., Lucka, Lothar, Donner, Peter, Reutter, Werner, Horstkorte, Rüdiger, Hinderlich, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134146/
https://ncbi.nlm.nih.gov/pubmed/15330759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040917
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