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Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.
A thorough mutational analysis of U6 RNA in combination with a functional reconstitution assay, revealed that three domains are important for U6 function in pre-mRNA splicing. In order to further analyze why these regions are so critical for splicing, we make use of phosphorothioate substituted U6 R...
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| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1992
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334015/ https://ncbi.nlm.nih.gov/pubmed/1641331 |
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