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Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.

A thorough mutational analysis of U6 RNA in combination with a functional reconstitution assay, revealed that three domains are important for U6 function in pre-mRNA splicing. In order to further analyze why these regions are so critical for splicing, we make use of phosphorothioate substituted U6 R...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Fabrizio, P, Abelson, J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1992
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1641331/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.14.3659
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