Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.
A thorough mutational analysis of U6 RNA in combination with a functional reconstitution assay, revealed that three domains are important for U6 function in pre-mRNA splicing. In order to further analyze why these regions are so critical for splicing, we make use of phosphorothioate substituted U6 R...
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| 發表在: | Nucleic Acids Res |
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| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1992
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| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1641331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.14.3659 |
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