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Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.

A thorough mutational analysis of U6 RNA in combination with a functional reconstitution assay, revealed that three domains are important for U6 function in pre-mRNA splicing. In order to further analyze why these regions are so critical for splicing, we make use of phosphorothioate substituted U6 R...

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Hlavní autoři: Fabrizio, P, Abelson, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC334015/
https://ncbi.nlm.nih.gov/pubmed/1641331
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