Protein Kinase C δ (PKCδ)-Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling Cascade Regulates Glycogen Synthase Kinase-3 (GSK-3) Inhibition-mediated Interleukin-10 (IL-10) Expression in Lipopolysaccharide (LPS)-induced Endotoxemia

Glycogen synthase kinase-3 (GSK-3) modulates a wide array of cellular processes, including embryonic development, cell differentiation, survival, and apoptosis. Recently, it was reported that a GSK-3 inhibitor attenuates lipopolysaccharide (LPS)-induced septic shock and regulates the mortality of en...

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Detalhes bibliográficos
Main Authors: Noh, Kyung Tae, Son, Kwang Hee, Jung, In Duk, Kang, Hyun Kyu, Hwang, Sun Ae, Lee, Won Suk, You, Ji Chang, Park, Yeong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340148/
https://ncbi.nlm.nih.gov/pubmed/22393041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308841
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