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Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases
Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with over 100 known substrates to deal with. How does GSK3 maintain control to selectively phosphorylate each substrate, and why was it evolutionarily favorable for GSK3 to assume such a large responsibility? GSK3 must be par...
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| Publié dans: | Pharmacol Ther |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340754/ https://ncbi.nlm.nih.gov/pubmed/25435019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.11.016 |
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