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Adenomatous Polyposis Coli (APC) Regulates Multiple Signaling Pathways by Enhancing Glycogen Synthase Kinase-3 (GSK-3) Activity
Glycogen synthase kinase-3 (GSK-3) is essential for many signaling pathways and cellular processes. As Adenomatous Polyposis Coli (APC) functions in many of the same processes, we investigated a role for APC in the regulation of GSK-3-dependent signaling. We find that APC directly enhances GSK-3 act...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2012
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281685/ https://ncbi.nlm.nih.gov/pubmed/22184111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323337 |
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