Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

Copy number variants (CNVs) are a recently recognized class of human germ line polymorphisms and are associated with a variety of human diseases, including cancer. Because of the strong genetic influence on prostate cancer, we sought to identify functionally active CNVs associated with susceptibilit...

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Autors principals: Demichelis, Francesca, Setlur, Sunita R., Banerjee, Samprit, Chakravarty, Dimple, Chen, Jin Yun Helen, Chen, Chen X., Huang, Julie, Beltran, Himisha, Oldridge, Derek A., Kitabayashi, Naoki, Stenzel, Birgit, Schaefer, Georg, Horninger, Wolfgang, Bektic, Jasmin, Chinnaiyan, Arul M., Goldenberg, Sagit, Siddiqui, Javed, Regan, Meredith M., Kearney, Michale, Soong, T. David, Rickman, David S., Elemento, Olivier, Wei, John T., Scherr, Douglas S., Sanda, Martin A., Bartsch, Georg, Lee, Charles, Klocker, Helmut, Rubin, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340033/
https://ncbi.nlm.nih.gov/pubmed/22496589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117405109
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