Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

Copy number variants (CNVs) are a recently recognized class of human germ line polymorphisms and are associated with a variety of human diseases, including cancer. Because of the strong genetic influence on prostate cancer, we sought to identify functionally active CNVs associated with susceptibilit...

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Detalhes bibliográficos
Main Authors: Demichelis, Francesca, Setlur, Sunita R., Banerjee, Samprit, Chakravarty, Dimple, Chen, Jin Yun Helen, Chen, Chen X., Huang, Julie, Beltran, Himisha, Oldridge, Derek A., Kitabayashi, Naoki, Stenzel, Birgit, Schaefer, Georg, Horninger, Wolfgang, Bektic, Jasmin, Chinnaiyan, Arul M., Goldenberg, Sagit, Siddiqui, Javed, Regan, Meredith M., Kearney, Michale, Soong, T. David, Rickman, David S., Elemento, Olivier, Wei, John T., Scherr, Douglas S., Sanda, Martin A., Bartsch, Georg, Lee, Charles, Klocker, Helmut, Rubin, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340033/
https://ncbi.nlm.nih.gov/pubmed/22496589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117405109
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