Učitavanje...

Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2″-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases

Enzymatic phosphorylation through a family of enzymes called aminoglycoside O-phosphotransferases (APHs) is a major mechanism by which bacteria confer resistance to aminoglycoside antibiotics. Members of the APH(2″) subfamily are of particular clinical interest because of their prevalence in pathoge...

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Bibliografski detalji
Glavni autori: Shi, Kun, Berghuis, Albert M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339986/
https://ncbi.nlm.nih.gov/pubmed/22371504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349670
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