Biochemical Characterization and N-terminomics Analysis of Leukolysin, the Membrane-type 6 Matrix Metalloprotease (MMP25): CHEMOKINE AND VIMENTIN CLEAVAGES ENHANCE CELL MIGRATION AND MACROPHAGE PHAGOCYTIC ACTIVITIES

The neutrophil-specific protease membrane-type 6 matrix metalloproteinase (MT6-MMP)/MMP-25/leukolysin is implicated in multiple sclerosis and cancer yet remains poorly characterized. To characterize the biological roles of MT6-MMP, it is critical to identify its substrates for which only seven are c...

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Bibliographische Detailangaben
Hauptverfasser: Starr, Amanda E., Bellac, Caroline L., Dufour, Antoine, Goebeler, Verena, Overall, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Genomics and Proteomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339980/
https://ncbi.nlm.nih.gov/pubmed/22367194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314179
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