TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation

Proteolytic processing is an irreversible post-translational modification functioning as a ubiquitous regulator of cellular activity. Protease activity is tightly regulated via control of gene expression, enzyme and substrate compartmentalization, zymogen activation, enzyme inactivation, and substra...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: King, Sarah L., Goth, Christoffer K., Eckhard, Ulrich, Joshi, Hiren J., Haue, Amalie D., Vakhrushev, Sergey Y., Schjoldager, Katrine T., Overall, Christopher M., Wandall, Hans H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961060/
https://ncbi.nlm.nih.gov/pubmed/29593093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001978
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