Deconstruction of O‐glycosylation—GalNAc‐T isoforms direct distinct subsets of the O‐glycoproteome

GalNAc‐type O‐glycosylation is found on most proteins trafficking through the secretory pathway in metazoan cells. The O‐glycoproteome is regulated by up to 20 polypeptide GalNAc‐Ts and the contributions and biological functions of individual GalNAc‐Ts are poorly understood. Here, we used a zinc‐fin...

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Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Schjoldager, Katrine T, Joshi, Hiren J, Kong, Yun, Goth, Christoffer K, King, Sarah Louise, Wandall, Hans H, Bennett, Eric P, Vakhrushev, Sergey Y, Clausen, Henrik
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693523/
https://ncbi.nlm.nih.gov/pubmed/26566661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540796
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