Deconstruction of O‐glycosylation—GalNAc‐T isoforms direct distinct subsets of the O‐glycoproteome

GalNAc‐type O‐glycosylation is found on most proteins trafficking through the secretory pathway in metazoan cells. The O‐glycoproteome is regulated by up to 20 polypeptide GalNAc‐Ts and the contributions and biological functions of individual GalNAc‐Ts are poorly understood. Here, we used a zinc‐fin...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Schjoldager, Katrine T, Joshi, Hiren J, Kong, Yun, Goth, Christoffer K, King, Sarah Louise, Wandall, Hans H, Bennett, Eric P, Vakhrushev, Sergey Y, Clausen, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693523/
https://ncbi.nlm.nih.gov/pubmed/26566661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540796
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