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Terminomics Reveals MMP2 Alters the Protease Web to Increase Vessel Permeability and Complement Activity in Skin Inflammation

During inflammation, local tissue responses are augmented by complement and acute phase proteins that exude into the tissue because of increased blood vessel permeability mediated by bradykinin, which is proteolytically released from kininogen. Moreover, proteases govern inflammatory responses by pr...

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Detalhes bibliográficos
Main Authors: auf dem Keller, Ulrich, Prudova, Anna, Eckhard, Ulrich, Fingleton, Barbara, Overall, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872078/
https://ncbi.nlm.nih.gov/pubmed/23322905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003512
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