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Genetic Dissection of Pyrimidine Biosynthesis and Salvage in Leishmania donovani

Protozoan parasites of the Leishmania genus express the metabolic machinery to synthesize pyrimidine nucleotides via both de novo and salvage pathways. To evaluate the relative contributions of pyrimidine biosynthesis and salvage to pyrimidine homeostasis in both life cycle stages of Leishmania dono...

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Hlavní autoři: Wilson, Zachary N., Gilroy, Caslin A., Boitz, Jan M., Ullman, Buddy, Yates, Phillip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339959/
https://ncbi.nlm.nih.gov/pubmed/22367196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346502
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