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CNGA3 Deficiency Affects Cone Synaptic Terminal Structure and Function and Leads to Secondary Rod Dysfunction and Degeneration

PURPOSE. To investigate rod function and survival after cone dysfunction and degeneration in a mouse model of cone cyclic nucleotide-gated (CNG) channel deficiency. METHODS. Rod function and survival in mice with cone CNG channel subunit CNGA3 deficiency (CNGA3(−/−) mice) were evaluated by electrore...

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Detalhes bibliográficos
Main Authors: Xu, Jianhua, Morris, Lynsie M., Michalakis, Stylianos, Biel, Martin, Fliesler, Steven J., Sherry, David M., Ding, Xi-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339899/
https://ncbi.nlm.nih.gov/pubmed/22247469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8168
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