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INSIGHT INTO THE MOLECULAR BASIS OF AROMATIC POLYKETIDE CYCLIZATION: CRYSTAL STRUCTURE AND IN VITRO CHARACTERIZATION OF WHIE-ORFVI()
Aromatic polyketides are biologically active natural products. Many important pharmaceuticals are derived from aromatic polyketides. Especially important in aromatic polyketide biosynthesis is the regiospecific cyclization of a linear, pre-assembled polyketide chain catalyzed by the aromatase/cyclas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339804/ https://ncbi.nlm.nih.gov/pubmed/22432862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201705q |
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