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Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes

The single recombinant expressing the Streptomyces coelicolor minimal whiE (spore pigment) polyketide synthase (PKS) is uniquely capable of generating a large array of well more than 30 polyketides, many of which, so far, are novel to this recombinant. The characterized polyketides represent a diver...

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Main Authors: Shen, Yuemao, Yoon, Pall, Yu, Tin-Wein, Floss, Heinz G., Hopwood, David, Moore, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC22344/
https://ncbi.nlm.nih.gov/pubmed/10097087
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