Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively

The assembly of the polyketide backbone of rifamycin B on the type I rifamycin polyketide synthase (PKS), encoded by the rifA–rifE genes, is terminated by the product of the rifF gene, an amide synthase that releases the completed undecaketide as its macrocyclic lactam. Inactivation of rifF gives a...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Tin-Wein, Shen, Yuemao, Doi-Katayama, Yukiko, Tang, Li, Park, Cheonseok, Moore, Bradley S., Richard Hutchinson, C., Floss, Heinz G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC17730/
https://ncbi.nlm.nih.gov/pubmed/10430893
Etiketler: Etiketle
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